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Dr. Hui-Kuo Shu

Hui-Kuo Shu MD


Professor, Department of Radiation Oncology, Emory University School of Medicine

Radiation Oncology

  • Brain & Spine

About the provider

Board certified in radiation oncology, Hui-Kuo Shu, MD, PhD, FASTRO, specializes in the treatment of brain and spine tumors. Dr. Shu has extensive expertise in the use of advanced radiotherapy techniques including intensity-modulated radiation therapy, stereotactic radiosurgery, fractionated stereotactic radiotherapy, extracranial radiosurgery and image-guided radiation therapy. He treats patients at Winship Cancer Institute and Emory Proton Therapy Center.

Dr. Shu was appointed assistant professor in radiation oncology at the University of Pennsylvania in 1999. He also served as the main radiation oncologist for the treatment of pediatric brain tumors at the Children’s Hospital of Philadelphia from 2001 to 2005. He was recruited to Emory University as a physician-scientist and was appointed associate professor in the department of radiation oncology in 2005.

Dr. Shu is a member of the Cancer Cell Biology research program at Winship Cancer Institute. He is a Fellow of the American Society for Radiation Oncology. He is also a member of the American Society for Clinical Oncology, Pediatric Brain Tumor Consortium, American Association for Cancer Research and Society for Neuro-Oncology, among other organizations.


Dr. Shu received his MD and PhD degrees in the NIH-sponsored Medical Scientist Training Program at Case Western Reserve University in Cleveland, Ohio. He completed post-graduate training with a year in internal medicine at University Hospitals of Cleveland, followed by a 5-year radiation oncology residency and fellowship at the University of California in San Francisco (UCSF).

At UCSF, he received grants from the American Society for Therapeutic Radiology and Oncology and the Radiological Society of North America to fund his fellowship research on malignant nervous system tumors. He was honored with awards and appointments during his training including the American Radium Society’s Young Oncologist Essay Award, the RSNA Roentgen Resident/Fellow Research Award at UCSF and chief resident in radiation oncology.


In the area of clinical research, Dr. Shu is a member of the neuro-oncology working group at Emory University and is actively conducting brain tumor-related clinical trials sponsored by the National Institutes of Health (NIH) directly and by cooperative groups such as NRG Oncology. His main research focus involves the study of glioblastomas and how to better treat these aggressive brain tumors. His most recent area of research interest involves development of novel MRI techniques that may be able to better identify infiltrative glial tumors and facilitate improved therapeutic targeting.

His research has been funded by the NIH and a number of brain tumor organizations including the Brain Tumor Foundation, American Brain Tumor Association, Childhood Brain Tumor Foundation and Southwest Brain Tumor Foundation.


He has published numerous articles in peer-reviewed journals including Proceedings of the National Academy of Sciences and Cancer Research. He also serves as a regular reviewer for several journals including Cancer Research and Cancer.


Dr. Shu has been listed consistently as one of Atlanta Magazine’s “Top Doctors” and appeared on the cover of the special issue in 2017.

Board Certifications

Radiation Oncology
American Board of Radiology, 1999